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Trilateral Project 24.1-Biotechnology 071

Among the concrete reasons is the reasoning, based on facts which are generally accepted by a person skilled in the art as scientifically or technologically correct, that such a person would be unable to extend the particular enabling description (i.e., mode for carrying out the invention) in the detailed description of the invention to the whole of the field within the extent (or the metes and bounds) of the claimed invention. (Implementing Guidelines I-1-3.2.3(2))

Preferably, the reasons of rejection should be supported by reference documents. (Implementing Guidelines I-1-3.2.3(3))